Anatomic Pathology Division
The Anatomic Pathology Division provides diagnosis
of diseases and monitoring of therapy by examining
tissues and cells, utilizing the latest techniques
for the diagnosis of neoplastic, inflammatory
and transplant-related diseases. The division
is divided into three sections: cytopathology,
medical pathology and surgical pathology.
Department
Vice Chair, University Services
David Elder,
MD
Department Vice Chair, Hospital Services
John E. Tomaszewski, MD
Services
Cytopathology
This section serves as a referral center for
diagnosis based on examination of cellular
material. Diseases of the thyroid, lung, gynecologic
organs, kidney and lymph nodes are evaluated.
Director
Prabodh K. Gupta, MD
Cytogenetics Laboratory
This laboratory performs chromosome analysis
in diagnosing and classifying leukemias and
other hematologic disorders.
Medical Pathology
This section diagnoses diseases at autopsy and
utilizes various techniques including electron
microscopy.
Director
Leslie A. Litzky, MD
Electron Microscopy
This laboratory examines tissues at high magnification to detect changes in cell components in the diagnosis of lung, renal and cardiac diseases as well as cancers of various organs. Element analysis by X-ray diffraction of small tissue samples is performed in association with electron microscopy to aid in interpretation.
Director
John E. Tomaszewski, MD
Surgical Pathology
This section is a referral center for diagnosis of malignant tumors of the breast, thyroid, uterus and ovaries, head and neck, lymphatic organs and lung. Diagnoses of neoplastic and non-neoplastic (inflammatory) diseases are also rendered.
Director
Antonia Sepulveda, MD
Immunopathology
This laboratory evaluates diagnostic specimens
using recent techniques to localize tumor antigens
in melanomas, carcinomas and sarcomas, including
intermediate filament protein and hormonal
markers such as keratin, alpha-fetoprotein,
human chorionic gonadotropin and calcitonin.
Reagents are available for localization of
various infectious agents.
Hematopathology
A joint program with the Molecular Flow Cytometry
and Cytogenetics Laboratories permits evaluation
of lymphoid tissue biopsies. Lymphoid lesions,
both nodal and extranodal, are studied extensively
by means of immuno-peroxidase staining, flow
cytometry and cytogenetics.
Metabolic Bone Laboratory
Non-neoplastic bone lesions, osteoporosis, and
nutritional bone disorders are evaluated qualitatively
and quantitatively.
Molecular Diagnosis
Solid tumor evaluation of small round cell tumors
and bone and soft tissue sarcomas is offered
in order to subclassify these lesions at the
genetic level.
Director
Frederic G. Barr, MD, PhD
Renal Pathology
Evaluation of kidney and urology diseases, transplant
rejection phenomena, and other disorders by
means of light microscopic immunofluorescence
and electron microscopy.
Vice Chair
John E. Tomaszewski, MD
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